A hybrid random forest deep learning classifier empowered edge cloud architecture for COVID-19 and pneumonia detectionResearch article Published on 2022-12-012022-10-05 Journal: Sensors (Basel, Switzerland) [Category] 치료기술, [키워드] Accuracy Affect Algorithm Classifier cloud computing complex computation conducted COVID-19 COVID19 CT scan dataset datasets deep deep learning detect diagnose effective Efficiency evaluate False positives forest global pandemic Healthcare industry heat Heat Transfer Search algorithm identify immunization inefficient Interaction less lung CT scan methodology offer outcomes overcome Patient Pneumonia predict PROTECT random Random forest resource Support the patient virus Web services X-ray [DOI] 10.1016/j.eswa.2022.118227 [Article Type] Research article
An efficient approach for SARS-CoV-2 monoclonal antibody production via modified mRNA-LNP immunizationArticle Published on 2022-11-052022-11-15 Journal: International journal of pharmaceutics [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] addition Antigen antigens applied approach approaches binding affinity circumvent complementary COVID-19 COVID-19 pandemic Delta Diseases evaluated functional fusion strategy generate immunization introduced lack Lipid Lipid nanoparticle (LNP) LNP mAb mAbs Membrane proteins methodology mice Modified mRNA monoclonal antibodies monoclonal antibody neutralize Neutralizing Neutralizing activity posttranslational modification Prophylactic Protein RBD Receptor binding domain SARS-CoV-2 SARS-CoV-2 RBD SARS-CoV-2 spike SARS-CoV-2 virus SARS-CoV-2. serum serum antibody several variants therapeutic drug Treatment Vaccines variants [DOI] 10.1016/j.ijpharm.2022.122256 PMC 바로가기
Intrinsic host susceptibility among multiple species to intranasal SARS-CoV-2 identifies diverse virological, biodistribution and pathological outcomesArticle Published on 2022-11-042022-11-15 Journal: Scientific Reports [Category] SARS, 진단, [키워드] administration airway analysed association Asymptomatic atraumatic biodistribution cardiovascular systems Cell consequence cynomolgus macaque cynomolgus macaques Disrupted exhibit exhibited hamster Host host susceptibility hosts identify Infection Infectious virus intranasal Lower respiratory tract lung Lung pathology methodology Microscopy Mild molecular morphology New World NHP non-human primate organelle outcome outcomes Pathogenesis pathological outcome pathology pathophysiological Post-infection Replication representing SARS-CoV-2 SARS-COV-2 infection susceptible ultrastructure Virological virus virus particle [DOI] 10.1038/s41598-022-23339-x PMC 바로가기
Cov-Net: A computer-aided diagnosis method for recognizing COVID-19 from chest X-ray images via machine visionResearch article Published on 2022-11-012022-10-05 Journal: Sensors (Basel, Switzerland) [Category] 진단, 치료기술, [키워드] Accuracy Algorithms applied asymmetric backbone build CAD Chest X-ray image Computer aided diagnosis (CAD) conditions Convolution Coronavirus disease 2019 COVID-19 database demonstrated Diagnosis Experimental result feature Feature learning global pandemic Image recognition information machine vision mechanism methodology outperform Perspective practicality recognizing robust selected Symptomatic patients [DOI] 10.1016/j.eswa.2022.118029 [Article Type] Research article
A computational approach to biological pathogenicityArticle Published on 2022-11-012022-11-15 Journal: Molecular genetics and genomics : MGG [Category] 바이오마커, [키워드] Accuracy adverse impact approach assessment Biochemistry Biomarkers clinical trial COVID-19 death Digital Digital genomic signature DNA DNA sequence energy event feature genomic Gibbs energy h-distance. Health Host humans hybridization machine machine learning machine learning model methodology microbe mitigate new strain oligonucleotide Other pandemic pathogen pathogenic Pathogenic relationship pathogenicity Pathogens/nonpathogens Perspective predict Quality reducing sensitivity Sensitivity and specificity Sickness specificity structural property [DOI] 10.1007/s00438-022-01951-w PMC 바로가기
Targeting SARS-CoV-2 papain-like protease in the postvaccine eraArticle Published on 2022-11-012022-11-15 Journal: Trends in pharmacological sciences [Category] SARS, 치료제, [키워드] approval artificial intelligence Compound computer-aided drug design COVID-19 Critical direct-acting antiviral drug drugs expected global healthcare Host innate immune response methodology Papain-like protease PLPro Rapid responses SARS-CoV-2 SARS-CoV-2 protein Small molecules small molecules. targeting therapeutic target Vaccine viral replication waning immunity while [DOI] 10.1016/j.tips.2022.08.008 PMC 바로가기
SARS-CoV-2 air and surface contamination in residential settingsArticle Published on 2022-10-272022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] absence Contamination COVID-19 patient determine evaluate fraction highest investigated Isolation methodology mild symptoms occur occurred Occurrence Particles performed persistence positive SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2-infected patient selected surface symptom onset the patient Transmission viability virus virus particle [DOI] 10.1038/s41598-022-22679-y PMC 바로가기
Comparison of the SARS-CoV-2 BD Veritor Nasal Antigen Test with Nasopharyngeal Reverse Transcription-PCR in Symptomatic PatientsArticle Published on 2022-10-262022-11-16 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, [키워드] Accuracy addition analyzed Antigen asymptomatic patient coronavirus COVID-19 cycle threshold Diagnosis diagnostic evaluated genes encoding immunochromatographic Infection information Interpretation methodology nasopharyngeal oropharyngeal swab Patient performed POC POC test point-of-care point-of-care test point-of-care testing provide rapid antigen test Rapid test rapid tests. reduce reproducibility reverse transcription-PCR RT-PCR Safe saline solution Sample SARS-CoV-2 sensitivity symptom onset symptomatic Symptomatic patients temperature Test tested the SARS-CoV-2 Variation Veritor test [DOI] 10.1128/spectrum.00190-22 PMC 바로가기
Brain-computer interface to predict impulse buying behavior using functional near-infrared spectroscopyArticle Published on 2022-10-262022-11-15 Journal: Scientific Reports [Category] 바이오마커, [키워드] Accuracy Activation average Biomarker Brain Evidence functional increase interface limitation memory methodology near-infrared spectroscopy predict previous study provide reduce reported responses Support Travel vaccination against COVID-19 [DOI] 10.1038/s41598-022-22653-8 PMC 바로가기
A pseudovirus-based platform to measure neutralizing antibodies in Mexico using SARS-CoV-2 as proof-of-conceptArticle Published on 2022-10-262022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] Accuracy antiviral immune response applied BSL-2 BSL-3 BSL-3 facilities evaluate evidenced functional in vitro Infection information Latin lentiviral particles Live virus Luminescence methodology NAb NAbs neutralizing antibody non-replicative Particle pathogen performed platform Protein pseudotyped lentiviral particles pseudovirus reporter resource Safe SARS-CoV-2 selected sensitivity serum samples specificity target cell transduced viral pathogen [DOI] 10.1038/s41598-022-22921-7 PMC 바로가기